Researchers Explore the Role Genetics Play in Shaping the Effects of Air Pollution on Lung Function in Adults with Asthma

In June 2026, a cross-sectional study was published in the eBioMedicine, a part of The Lancet, exploring how genetic differences may shape the effects of air pollution on lung function in adults with asthma. Researchers analyzed data on 948 adults with asthma from the Severe Asthma Research Program (SARP). The results showed that higher exposure to fine particulate matter (PM2.5) was associated with lower lung function. The researchers also identified several genetic variants that increased susceptibility to the harmful effects of air pollution, highlighting the importance of considering not only environmental exposures but also genetics in asthma treatment.  

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Regional Asthma Management and Prevention
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