The IMAGINE study utilized a three-phased randomized control trial in children to understand the often assumed correlation of adherence and technique. The results were published in the 2025 article The Correlation Between the Level of Therapy Adherence and Inhalation Technique in Children with Uncontrolled Asthma Using a Smart Inhaler: The IMAGINE Study, Results from 32 participants aged 6–18, who successfully completed Phase I, revealed no significant correlation between adherence and technique, challenging the assumption that these two factors are closely linked. Poor inhalation technique was associated with age, height, rescue medication use, and more ER visits. Meanwhile, good adherence was also linked to ER visits. The findings highlight the need for pediatric asthma management to address adherence and technique separately with targeted, personalized interventions.
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